JD Supra

Frequentist or Bayesian? All Roads Lead to Smarter Trials with FDA’s New Bayesian Guidance

Jessica Ritsick, Yifan Wang, Ph.D. Our FDA: Drug & Device Team analyzes the Food and Drug Administration’s new guidance on Bayesian approaches to innovative drug trials, providing greater clarity on ...
Nature

Empirical Bayesian Methods in Statistical Inference

Empirical Bayesian methods occupy a unique position at the interface of frequentist and Bayesian paradigms by estimating prior distributions directly from observed data. This approach preserves the ...
Reason

How To Speed Up the Search for Cures Through a Change in Probability Theory

Marty Makary was appointed commissioner of the Food and Drug Administration (FDA) in 2025. The prominent surgeon, medical researcher, bestselling author, and critic of the medical ...
Nature

Fiducial Inference in Statistical Modeling

Fiducial inference is a framework for assigning a probability distribution to an unknown parameter on the basis of observed data and a statistical model alone, without invoking a prior distribution.