Cells are the fundamental unit of life. The average human body contains around 30 trillion cells with varying functions and potentials. Communication between cells is central to the body’s ability to ...

Cells sense external mechanical forces through cadherins (which form cell–cell adhesions) and integrins (which form cell–matrix adhesions). Vinculin (VCL) accumulates at both types of adhesions, where ...

The immune system plays a dual role in inflammation and cancer development. Immune system effector cells quickly identify and destroy malignant cells, but immune system-mediated inflammation regulates ...

EMT facilitates cell mobility and the migration of epithelial cells that have gained mesenchymal characteristics, notably the loss of adherins (specifically E-cadherins) and the loss of cell polarity.

The immune system plays a dual role in inflammation and cancer development. Immune system effector cells rapidly recognize and kill malignant cells; meanwhile, immune system-mediated inflammation ...