Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...

Autophagy is essentially the 'rubbish collection' of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest ...

In certain contexts, the Notch receptor may participate in “reverse signaling,” influencing neighboring cells directly.

A team at Huntsman Cancer Institute at the University of Utah (the U) has uncovered a previously unrecognized molecular ...

Confronting the central challenge of how necroptosis reconciles high sensitivity to stimuli with robustness against intrinsic ...

Calcium is widely known for its role in maintaining strong bones and teeth, but it is also one of the body's most important ...

The distinct aging rates of neural progenitor cells and Wnt signaling dictate mammalian cortical layer proportions.

A team at Huntsman Cancer Institute at the University of Utah (the U) has uncovered a previously unrecognized molecular mechanism by which cells send signals to one another-insight that could help ...

A new review brings attention to the STING pathway as a critical regulator in both colitis and colon cancer, highlighting its complex and often opposing roles in inflammation and tumor development.

For most children diagnosed with medulloblastoma, the most common malignant pediatric brain tumor, survival rates are ...