Please can you give us a brief overview of the miniaturization of columns in chromatography? The miniaturization of columns in chromatography originated with the theoretical work of Marcel Golay on ...

Downstream bioprocessing steps have long been a challenge to drug manufacturers, particularly the chromatography step for purification of monoclonal antibodies (mAbs). The complexity of traditional ...

Case in point: For more than a century, chromatography practitioners have been separating the components of chemical mixtures by using columns packed with various types of particulate matter. Recently ...

Simulated moving bed chromatography uses a counter-current to allow continuous chromatographic separations, which allows researchers to extract more analyte whilst using less packing material and ...

Reviewed by Dr. Catherine Shaffer, Ph.D. Chiral column chromatography makes use of the concept of chirality. Chirality relates to study of the three-dimensional structure of molecules. The term comes ...

Affinity chromatography can be applied to a wide array of proteins and works by exploiting the binding properties between proteins and ligands. It involves passing a recombinant protein mixture over a ...