Digital breast tomosynthesis (DBT) screening supplemented by MRI for women with dense breasts led to both greater benefits and increased harms in a model-based comparative effectiveness analysis.

It is clear to all informed persons that the nation needs better evidence of what works in health care, and this has propelled comparative effectiveness research (CER) policy developments of late.

In a recent scientific paper published in the journal Nature Microbiology, researchers reproduced two target trials using electronic health records (EHRs) of the Department of Veterans Affairs (VA) to ...

The Patient-Centered Outcomes Research Institute (PCORI) today announced funding awards totaling $208 million to support 17 new comparative clinical effectiveness research (CER) studies, including ...

The European Medicines Agency has finalized its reflection paper on a tailored clinical approach to biosimilar development, ...

Rates of physician skin examinations increased significantly from baseline to 12 months in all three intervention groups: PAE, 24%-39%, relative risk [RR], 1.65, 95% ...

The comparative effectiveness of glucose-lowering medications for use with metformin to maintain target glycated hemoglobin levels in persons with type 2 diabetes is uncertain. In this trial involving ...

Real-world comparative outcomes of chemo-immunotherapy versus chemotherapy in colon cancer: A multi-center retrospective cohort study. This is an ASCO Meeting Abstract from the 2025 ASCO Annual ...

The safety profiles of several commonly used advanced therapies for Crohn’s disease appear similar, with no significant differences observed in risks for serious infections and cardiovascular adverse ...

CHICAGO (Reuters) - Two standard treatments for hepatitis C work equally well at knocking down the virus for most patients, U.S. researchers reported on Wednesday. The findings, from a 3,000-patient ...