The evaluation of new drugs designed to treat specific anemias should include a thorough understanding of underlying pathophysiology, with a focus on enhancing oxygen transport. In this concise review ...

Oxidative degradation of high-energy substrates is an essential feature of all living organisms. Aerobic organisms have developed complex chemical reactions, grouped under the term 'respiratory chain' ...

Hypoxemia (including intermittent hypoxemia) in premature infants has detrimental effects on neurodevelopment and other sequelae. Not only is the total duration of time spent in the hypoxemic range a ...

The most common indication for the administration of supplemental oxygen is acute or chronic hypoxemia. Causes include pulmonary infection, chronic obstructive pulmonary disease (COPD), congestive ...