An Adelaide-based research collaboration has identified the specific nerve pathways responsible for relaying pain signals from the bowel to the brain, paving the way for new irritable bowel syndrome ...

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...

Pain isn't just a physical sensation—it also carries emotional weight. That distress, anguish, and anxiety can turn a fleeting injury into long-term suffering. Subscribe to our newsletter for the ...

Scientists created a model of the human pain pathway in a dish by connecting four separate brain organoids. The feat should help them understand sensory disorders like those affecting pain perception.

Editor’s Note (1/31/25): The U.S. Food and Drug Administration has approved the novel nonopioid medication suzetrigine for acute pain. That pain ranges from moderate to severe. The drug was tested in ...

Scientists have discovered a brain circuit that gives pain its emotional sting, explaining why some hurts linger as suffering. The breakthrough challenges our beliefs about how we process pain and may ...

Stanford Medicine investigators have replicated, in a lab dish, one of the most prominent human nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to the ...

Four tiny 3D organs connected themselves in a lab dish, forming a replica of the human pain pathway, in a new study. The discovery allows scientists to better understand chronic pain and how pain ...

Pain isn't just a physical sensation-it also carries emotional weight. That distress, anguish, and anxiety can turn a fleeting injury into long-term suffering. Researchers at the Salk Institute have ...

The new method is designed to focus specifically on pain-related signals, without interfering with normal activity in other parts of the brain. A new preclinical study has identified a gene therapy ap ...

Salk scientists uncover a key neural circuit in mice that gives pain its emotional punch, opening new doors for treating fibromyalgia, migraine, and PTSD LA JOLLA (July 9, 2025)—Pain isn’t just a ...