Genes encode proteins and proteins dictate cell function. Therefore, the thousands of genes expressed in a particular cell determine what that cell can do. Moreover, each step in the flow of ...
Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.
Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene ...
DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning ...
Gene expression experiments measure changes in RNA transcript levels to compare how genes are up- or down-regulated across ...
Researchers developed e2MPRA, a high-throughput technique that simultaneously measures cis-regulatory element activity and ...
Primary immunodeficiencies are genetic disorders that impact on the immune system due to defective function of a variety of genes. Among those molecules are ...
Epigenetics is the study of various heritable alterations that control gene expression without changing the DNA sequence. 1 The name epigenetics comes from the Greek prefix “epi”, which means on top ...
KLF5 appears to fuel pancreatic cancer metastasis by reprogramming epigenetic controls, offering a potential new therapeutic target.
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