When chemists design drug candidates, shape matters enormously. Many active pharmaceutical ingredients contain branched ...

A team of chemists has unveiled a novel method to simplify the synthesis of piperidines, a key structural component in many pharmaceuticals. The study combines biocatalytic carbon-hydrogen oxidation ...

Recreating natural molecules in the laboratory as part of the search for potential new drugs for disease can be difficult, costly and slow. The problem? Many chemical processes tend to produce not ...

Chemists have synthesized the first stable molecule whose chirality is solely attributed to a stereogenic oxygen, according to a new study (Nature 2023, DOI: 10.1038/s41586-023-05719-z). Though carbon ...

The first and the best-known metallocene is "ferrocene," which contains a single iron atom. Today, sandwich complexes can be found in many inorganic chemistry textbooks, and the bonding and electronic ...