Escherichia coli remains at the forefront of recombinant protein production, owing to its rapid growth, well-characterised genetics and the ease with which it can be genetically manipulated. The ...

Bacillus subtilis has emerged as a pre‐eminent model organism for the study and application of protein expression and secretion, owing to its robust secretory pathways and genetic tractability. Its ...

The cost-effective, easy-to-use T7 expression system has been integral to Escherichia coli protein production since its introduction in 1986. Now, a just-developed enhancement is making it even better ...

The Expi293™ PRO Expression System is a high-performance transient HEK293 mammalian protein expression platform designed to help researchers express more proteins faster, at higher yields, and with ...

In the evolving fields of genomics and protein expression, staying updated with the latest advancements is essential. This eBook offers a handpicked collection of posters at the ELRIG Drug Discovery ...

To enhance CAR T therapies, scientists are actively studying TCR signaling and T-cell exhaustion mechanisms to improve CAR T persistence and function. Additionally, there is a growing trend towards ...

Codon optimization is a central strategy in recombinant protein production, enabling genes from one organism to be efficiently expressed in another. Conventional methods typically replace ...

A single genetic abnormality found in more than two-thirds of supratentorial ependymomas, a deadly class of pediatric brain tumors, does far more than activate one inflammatory pathway. The ZFTA-RELA ...

Impact of lorlatinib dose modifications on adverse event outcomes in the phase 3 CROWN study. RC108 in combination with furmonertinib in patients with locally advanced or metastatic EGFR-mutated ...