Bile is a greenish-yellow liquid made and released by the liver and stored in the gallbladder. It aids in the digestion of food and fluids by breaking down fats into fatty acids. Your body then takes ...

(A) The classic bile acid synthesis pathway: cholesterol 7α-hydroxylase (CYP7A1) converts cholesterol to 7α-hydroxycholesterol (7α-HOC). The sterol 12α-hydroxylase (CYP8B1) converts the intermediate ...

Bile acids are essential to digestion, by acting like a kind of detergent that breaks up fat molecules. Fat doesn't dissolve in water, but our digestive system is full of water, so the fat we consume ...

DEAR MAYO CLINIC: What is the difference between bile reflux and acid reflux? Bile reflux involves fluid from the small intestine flowing into the stomach and esophagus. Acid reflux is backflow of ...

DEAR DR. ROACH: I’m a 67-year-old female in pretty good health. The only medications I take are for my thyroid, arthritis and hormone replacement. Early last year, I was sick with a cold/flu for a ...

Efforts to raise gut health awareness, including the ‘blue poop challenge’, have recently made quite a, *ahem*, splash across social media. Participants eat dyed muffins to measure their individual ...

Not all probiotics are created equal. In a new study, researchers found that certain enzymes within a class known as bile salt hydrolases (BSHs) can restrict Clostridioides difficile (C. diff.) ...

Probiotic Lactobacillus bacteria use enzymes situationally to manipulate bile acids and promote their own survival in the gut. New research from North Carolina State University reveals that probiotic ...

In medicine, treatment goals set by physicians might differ from patient priorities. Although normalisation of laboratory parameters is a target supported by outcomes data, patient perspectives ...

Colesevelam was superior to placebo in inducing remission in patients with bile acid diarrhea with no serious adverse events reported, according to results published in The Lancet Gastroenterology & ...