A healthy 8-year-old boy presented to our dermatology clinic with a 4-week history of worsening movement limitation and pain due to skin retraction of the right axilla. There were no constitutional ...

A 34-year-old woman (gravida 3, para 2) at 16 weeks’ gestation was found to have platelets unable to be quantified because of clumping on routine prenatal blood work, with a visual estimate of 40 ...

Key points The definition and criteria used for reporting stillbirths in Canada are idiosyncratic and dated, and directly responsible for the country’s artificially high and rising stillbirth rate ...

Pre-exposure prophylaxis (PrEP) involving daily tenofovir disoproxil fumarate/emtricitabine 300/200 mg, taken orally, is a highly effective strategy for reducing the risk of HIV acquisition in adults ...

Defined as troponin elevation exceeding the 99th percentile of reference values within 30 days of noncardiac surgery due to ischemia, the estimated incidence is 12%–24% and is higher after nonelective ...

In June 2026, 2 Canadian cities will host several FIFA World Cup soccer matches. Health care systems may have to play host too, as large numbers of visitors to these cities will increase pressure on ...

Background: Ground-level falls are common among older adults and are the most frequent cause of traumatic intracranial bleeding. The aim of this study was to derive a clinical decision rule that ...

Intramuscular epinephrine rapidly reverses airway edema and shock.[1][1] Current evidence does not support use of antihistamines and corticosteroids to prevent progression of anaphylaxis or biphasic ...

Eustachian tube dysfunction leads to inadequate ventilation of the middle ear It is caused by inflammation or narrowing of the eustachian tube, which leads to aural fullness and muffled hearing ...

Key points A 75-year-old woman presented to the emergency department with acute confusion and lethargy on the third day of ...

“Failure to cope” is a label applied to patients who cannot function at home, sometimes because of new medical problems, but often owing to unaddressed chronic medical or social issues. The underlying ...

The prevalence rises with age, reaching 5% to 7% among patients older than 70 years.[1][1] The differential diagnosis of an adrenal mass includes adenomas (both functional and nonfunctional), ...