Parkinson’s disease (PD) is a common neurodegenerative disorder that is mainly caused by dopaminergic neuron loss in the substantia nigra. Several nuclear medicine radiotracers have been developed to ...
4 Parkinson's Disease Research, Education and Clinical Centers (PADRECC), Philadelphia Veterans Affairs Medical Center, Philadelphia, Pennsylvania, USA 5 Mental Illness Research, Education and ...
Researchers have developed an AI-powered MRI system that can diagnose Parkinson’s disease and its atypical variants with an astonishing 98% accuracy. This cutting-edge system, known as Automated ...
Background Isolated rapid eye movement (REM) sleep behaviour disorder (iRBD) is a prodromal state of clinical α-synucleinopathies such as Parkinson’s disease and Lewy body dementia. The lead-time ...
Abstract: Striatum segmentation on dopamine transporter (DaT) SPECT is necessary to quantify striatal uptake for Parkinson’s disease (PD), but is challenging due to the inferior resolution. This work ...
Journal of Nuclear Medicine July 2024, jnumed.124.267570; DOI: https://doi.org/10.2967/jnumed.124.267570 Convolutional neural networks (CNNs) outperform conventional ...
SPECT of striatal dopamine transporter (DAT) availability with N-ω-fluoropropyl-2β-carbomethoxy-3β-(4-123 I-iodophenyl)nortropane ([123 I]FP-CIT) is widely used to support the diagnostic work-up in ...
Background: Dopamine transporter single-photon emission computed tomography (DAT-SPECT) is a crucial tool for evaluating patients with Parkinson’s disease (PD). However, its implication is limited by ...
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