eLife

A proteome-wide biochemical screen defines binding determinants of the core autophagy protein LC3B

Human MAP1LC3B (LC3B) binds proteins involved in autophagy and other cellular processes using a degenerate four-residue short linear motif known as the LC3-interacting region (LIR). Biochemical and ...

Technical View: Bears may get charge if Nifty decisively breaks 25,800, until then hope for 26,000 remains; Bank Nifty outperforms, holds 60,500

Weekly options data continued to suggest that 26,000 is expected to be immediate crucial resistance for the Nifty 50, with immediate support at 25,800.

Technical View: 26,000 to be crucial for further upside in Nifty 50, till then consolidation likely; India VIX cools; Bank Nifty ends three-day rally

India VIX, the volatility index, declined by 4.31 percent to 11.67 and slipped below all key moving averages, signalling increased comfort for bulls. As long as the VIX sustains below the 12 zone, ...
Nature

Crystal structure of the bacterial conjugation repressor FinO

Figure 1: Stereo view of electron density maps around residues 152–156 (on strand β4) with the final 2.0 Å refined model superimposed. Our model assumes that the conformation of FinO does not change ...
Nature

Crystal structure of the Holliday junction resolving enzyme T7 endonuclease I

We have solved the crystal structure of the Holliday junction resolving enzyme T7 endonuclease I at 2.1 Å resolution using the multiwavelength anomalous dispersion (MAD) technique. Endonuclease I ...