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Active vision dynamically refines spatiotemporal neural representations, optimising visual processing through scanning behaviour and non-associative learning, providing insights into efficient sensory ...
Insects possess a remarkable ability to develop innate immune memory, and the mechanisms underlying this process are becoming a central topic in innate immunity research.
This important study uses long-term behavioural observations to understand the factors that influence female-on-female aggression in gorilla social groups. The evidence supporting the claims is ...
Large-scale microscopy combined with tissue clearing and expansion enables nanoscale imaging of centimeter scale specimens.
This is an important study that combines replications of findings and novel detailed MRI investigations to assess the impact of environmental enrichment and maternal behavior on mice brain structure ...
The mRNA metabolism passively shapes the levels of an mRNA modification called m6A within a steady-state cell and upon stress.
Liquid-liquid phase separation (LLPS) has emerged as a major organizing principle in cells. Recent work showed that multiple components of integrin-mediated focal adhesions, including p130Cas can form ...
Trained immunity is a form of innate immune cell memory that is being developed as a novel immunotherapeutic approach for cancer treatment.
The tumor suppressor p53 is a transcription factor that controls the expression of hundreds of genes. Emerging evidence suggests that the p53-induced RNA-binding protein ZMAT3 is a key splicing ...
This valuable study identifies asymmetric dimethylarginine (ADMA) histones as potential determinants of the initial genomic binding of Rhino, a Drosophila-specific chromatin protein essential for ...
Mutations in EGLN1, the gene encoding for hypoxia-inducible factor (HIF) prolyl-4-hydroxylase 2 (PHD2), cause erythrocytosis and in rare cases the development of neuroendocrine tumors. In the presence ...
Almost all cervical cancers are caused by human papillomaviruses (HPVs). In most cases, HPV DNA is integrated into the human genome. We found that tumor-specific, HPV-human DNA junctions are ...