Ions play a vital role in regulating the antitumoral functions of immune cells within the tumor microenvironment (TME). Protons, derived from endogenous ...

Every time our body encounters a new disease-causing agent, a crucial defence system called adaptive immunity comes into play. T cells, the top agents ...

The anti-tumor immune response involves a series of complex steps mediated by various immune cells and signaling molecules.

CK0804 is a first in class, CXCR4hi Treg therapeutic designed to preferentially traffic towards its ligand CXCL12 over expressed in the bone marrow and ...

In a new study, people who incorporated a fermented side dish into their weekly routine saw meaningful shifts in immune cells that help the body fight infections.

This article and associated images are based on a poster originally authored by Alex Chenchik, Lester Kobzik, Tianbing Liu, Dongfang Hu, Kitt Paraiso, Khadija Ghias, and Paul Diehl and presented at ...

A new groundbreaking study has recently identified the link between the long-standing mystery in autoimmune disease: Epstein-Barr Virus (EBV) and how it contributes towards the development of systemic ...

About five million people worldwide have systemic lupus erythematosus (SLE), an autoimmune disease that damages organs and tissues throughout the body, including skin, joints, kidneys, heart, and ...

A NEW major study has uncovered how the Epstein–Barr virus (EBV) may directly contribute to the onset and progression of systemic lupus erythematosus (SLE). For decades, researchers have known that ...

Background: Hypertension remains the leading cause of mortality worldwide. Aim: We hypothesize that ENaC-dependent sodium entry triggers inflammation and activates the Keap1-Nrf2 signaling axis in ...