🩸 Tranexamic Acid (TXA) – How does it actually work? When trauma patients bleed, their body forms clots to stop the loss. But the body also activates fibrinolysis – the natural breakdown of clots. In major haemorrhage this can become overactive, leading to clot breakdown before bleeding is controlled. 👉 TXA works by blocking plasminogen from converting into plasmin, the enzyme that dissolves fibrin clots. 👉 This helps stabilise clots, reduce bleeding, and improve survival if given within 3 ho
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JC: Can we give tranexamic acid (TXA) via the IM route? St Emlyn's
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Most underrated active for skin lightening? Tranexamic acid (TXA) is a skincare active that can be used to treat hyperpigmentation and melasma, and some say it's safer and more effective than other brightening agents like retinol, hydroquinone, and vitamin C. TXA works by inhibiting tyrosinase, the enzyme that produces darkening pigment, and by interfering with melanin production. It can also help calm the skin and restore the skin barrier. | Dr Lim Ing Kien
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