Reconstitution of a Transmembrane Protein, the Voltage-gated Ion Channel, KvAP, into Giant Unilamellar Vesicles for Microscopy and Patch Clamp Studies

• What is the difference between a gated ion channel and a leak channel?Explain the role of each type of channel in neuronal cell function.• Explain the sequence in which ion channels open and close to propagate anaction potential.• Draw a sketch of the Potential Chart that shows an action potential. Label thechart to show where sodium and potassium gated channels open and close.

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Video: Reconstitution of a Transmembrane Protein, the Voltage-gated Ion Channel, KvAP, into Giant Unilamellar Vesicles for Microscopy and Patch Clamp Studies

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